Genetics and Complex Diseases

The complex interplay of biological processes with environmental factors as they apply to chronic, multigenic, and multifactorial diseases is the focus of the Department of Genetics and Complex Diseases. Department faculty aim to elucidate the molecular mechanisms underlying the intricate interaction between genetic determinants and their divergent responses to environmental signals to affect the health of human populations. Research focuses on several broad categories, including metabolism, stress response and inflammatory signaling. Areas of study include diseases such as diabetes and cancer, disease-risk conditions such as obesity, age-related (chronic) diseases, and the normal aging process. These are investigated both at the mechanistic level and in the context of population studies.